SCHEMBL14898534

SCHEMBL14898534

CNc1nc2c(cnn2C)c(=O)[nH]1

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
PDE2A O00408 1/20 0.46
PDE9A O76083 18/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1520569 0.80 PDE9A (0.46) ALDH1A1PDE9A
SCHEMBL16981631 0.80 PDE9A (0.53) PDE9A
SCHEMBL889723 0.78 CDK4 (0.55) ALDH1A1PDE2APDE9A
SCHEMBL3424725 0.77 ALDH1A1 (0.51) ALDH1A1PDE2APDE9A
SCHEMBL889777 0.77 ALDH1A1 (0.56) ALDH1A1PDE2A
SCHEMBL8114828 0.77 ALDH1A1 (0.51) ALDH1A1PDE2APDE9A
SCHEMBL16981644 0.77 PDE9A (0.74) PDE9A
SCHEMBL16981636 0.76 PDE9A (0.77) ALDH1A1PDE2APDE9A
SCHEMBL17889340 0.74 LMNA (0.56) ALDH1A1
SCHEMBL20257497 0.74 ALDH1A1 (0.49) ALDH1A1PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8431366-B2 Modified oligonucleotides and applications thereof APPLIED BIOSYSTEMS, LLC (US) 2013-04-30 US disclosed