Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14898563 | 1.00 | RAB9A (0.50) | RAB9AS1PR1S1PR3S1PR5POLB | |
| SCHEMBL10141474 | 0.94 | RAB9A (0.57) | RAB9AS1PR1S1PR3S1PR5POLB | |
| SCHEMBL17627000 | 0.87 | S1PR1 (0.48) | S1PR1S1PR3S1PR5MEN1TP53 | |
| SCHEMBL8800154 | 0.86 | RAB9A (0.53) | RAB9APOLBMEN1TP53KMT2A | |
| SCHEMBL10119377 | 0.83 | RAB9A (0.57) | RAB9APOLBMEN1KMT2AHTT | |
| SCHEMBL1146693 | 0.83 | RAB9A (0.56) | RAB9APOLBMEN1KMT2AHTT | |
| SCHEMBL28064109 | 0.83 | RAB9A (0.58) | RAB9APOLBMEN1MAPTKMT2A | |
| SCHEMBL10142030 | 0.81 | S1PR1 (0.45) | RAB9AS1PR1S1PR3S1PR5POLB | |
| SCHEMBL9978245 | 0.80 | RAB9A (0.58) | RAB9APOLBMEN1KMT2AHTT | |
| SCHEMBL4541731 | 0.80 | RAB9A (0.58) | RAB9APOLBMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431576-B2 | Heterocyclic compounds for the treatment of neurological and psychological disorders | ALKERMES PHARMA IRELAND LIMITED (IE) | 2013-04-30 | — | — | US | disclosed |