Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360692 | 0.95 | RAB9A (0.64) | RAB9APOLBL3MBTL1HTTTSHR | |
| SCHEMBL1146693 | 0.88 | RAB9A (0.56) | RAB9APOLBL3MBTL1HTTTSHR | |
| SCHEMBL28064109 | 0.88 | RAB9A (0.58) | RAB9APOLBL3MBTL1HTTTSHR | |
| SCHEMBL4541731 | 0.88 | RAB9A (0.58) | RAB9APOLBHTTTSHRALDH1A1 | |
| SCHEMBL8800154 | 0.86 | RAB9A (0.53) | RAB9APOLBL3MBTL1HTTTSHR | |
| SCHEMBL9978311 | 0.85 | RAB9A (0.56) | RAB9APOLBL3MBTL1HTTTSHR | |
| SCHEMBL4576862 | 0.83 | RAB9A (0.64) | RAB9APOLBL3MBTL1HTTTSHR | |
| SCHEMBL11993036 | 0.81 | RAB9A (0.61) | RAB9APOLBHTTTSHRALDH1A1 | |
| SCHEMBL10120835 | 0.81 | RAB9A (0.61) | RAB9APOLBL3MBTL1HTTTSHR | |
| SCHEMBL80443 | 0.81 | RAB9A (0.51) | RAB9APOLBHTTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |