Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5090901 | 0.80 | GABRA1 (0.43) | ERN1POLBGAARAB9AALDH1A1 | |
| SCHEMBL8029412 | 0.80 | ERN1 (0.60) | ERN1POLBGAARAB9AALDH1A1 | |
| SCHEMBL49998 | 0.79 | — | — | |
| SCHEMBL29419973 | 0.79 | — | — | |
| SCHEMBL308223 | 0.79 | ERN1 (0.65) | ERN1POLBGAARAB9AALDH1A1 | |
| SCHEMBL6035511 | 0.77 | TRIM24 (0.54) | POLBGAARAB9AALDH1A1HPGD | |
| SCHEMBL31345759 | 0.77 | TRIM24 (0.54) | POLBGAARAB9AALDH1A1HPGD | |
| SCHEMBL7172431 | 0.77 | TRIM24 (0.54) | POLBGAARAB9AALDH1A1HPGD | |
| SCHEMBL1471372 | 0.77 | TRIM24 (0.54) | POLBGAARAB9AALDH1A1HPGD | |
| SCHEMBL6152406 | 0.77 | TRIM24 (0.54) | POLBGAARAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431110-B2 | Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators | HMI MEDICAL INNOVATIONS, LLC. (US) | 2013-04-30 | — | — | US | disclosed |