Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7137843 | 0.85 | HNF4A (0.48) | ALDH1A1HPGDHSD17B10AKR1B1HDAC4 | |
| SCHEMBL14899338 | 0.80 | ERN1 (0.60) | ERN1GAAPOLBRAB9ALMNA | |
| SCHEMBL20866822 | 0.77 | PARP1 (0.41) | POLBLMNAALDH1A1 | |
| SCHEMBL19782076 | 0.76 | ALDH1A1 (0.56) | GABRA1GABRB2ERN1GAAPOLB | |
| SCHEMBL15032224 | 0.76 | TSHR (0.39) | ERN1GAAPOLBRAB9ALMNA | |
| SCHEMBL31152506 | 0.75 | ERN1 (0.67) | GABRA1GABRB2ERN1LMNAALDH1A1 | |
| SCHEMBL16439936 | 0.75 | ERN1 (0.67) | GABRA1GABRB2ERN1LMNAALDH1A1 | |
| SCHEMBL5463687 | 0.72 | ALDH1A1 (0.52) | LMNAALDH1A1CA1CA2MMP2 | |
| SCHEMBL10054715 | 0.72 | TLR2 (0.67) | ERN1GAAPOLBRAB9ALMNA | |
| SCHEMBL21883548 | 0.72 | BACE1 (0.36) | ERN1GAAPOLBRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435701-B2 | Catalytic composition and its preparation and use for preparing polymers from ethylenically unsaturated monomers | ROHM AND HAAS COMPANY (US) | 2008-10-14 | — | — | US | disclosed |
| EP-1728553-A2 | A catalytic composition comprising a neutral metal-pair complex and its preparation and use for preparing polymers from ethylenically unsaturated monomers | Rohm and Haas Company (US) | 2006-12-06 | — | — | EP | disclosed |
| US-20060270811-A1 | Catalytic composition and its preparation and use for preparing polymers from ethylenically unsaturated monomers | ROHM AND HAAS COMPANY | 2006-11-30 | — | — | US | disclosed |