Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HBB | P68871 | 1/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.38 |
| ▸ | KDM5A | P29375 | 4/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265266 | 0.90 | TSHR (0.57) | TSHRTDP1MAPTALDH1A1LMNA | |
| SCHEMBL13137722 | 0.89 | — | — | |
| SCHEMBL11472367 | 0.88 | MAPT (0.62) | TSHRTDP1MAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1919723 | 0.86 | TSHR (0.68) | TSHRTDP1MAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11465486 | 0.85 | TSHR (0.65) | TSHRTDP1MAPTALDH1A1LMNA | |
| SCHEMBL78617 | 0.85 | DNM1 (0.47) | TSHRLMNAS1PR2S1PR1S1PR3 | |
| SCHEMBL17309881 | 0.82 | — | — | |
| Bromide SCHEMBL8466957 | 0.82 | TSHR (0.62) | TSHRTDP1MAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1997515 | 0.82 | DNM1 (0.50) | TSHRLMNATP53HTTHBB | |
| Bromide SCHEMBL1993994 | 0.82 | DNM1 (0.50) | TSHRLMNAS1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9174958-B2 | Process for the preparation of dronedarone | SANOFI (FR) | 2015-11-03 | — | — | US | disclosed |
| US-20130109868-A1 | Process for the Preparation of Dronedarone | SANOFI (FR) | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109868-A1 | Process for the Preparation of Dronedarone | CYP2D6, CYP2B6, CYP2F1 | TSHR 4058/4885TDP1 2601/4885MAPT 4369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.