SCHEMBL14901082

SCHEMBL14901082

OC(c1cccc(-n2c3ccccc3c3ccccc32)c1)(c1cccc(-n2c3ccccc3c3ccccc32)c1)c1ccccc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ ATM Q13315 1/20 0.44
▸ KMT2A Q03164 3/20 0.35
▸ NPC1 O15118 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ HTR7 P34969 1/20 0.34
▸ MAPK14 Q16539 1/20 0.33
▸ PLA2G10 O15496 1/20 0.33
▸ IL1R1 P14778 1/20 0.33
▸ CYP11B2 P19099 1/20 0.32
▸ FOLH1 Q04609 1/20 0.32
▸ MEN1 O00255 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ GAA P10253 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ DUSP3 P51452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14901090 0.87 KDM4E (0.39) L3MBTL1KDM4EATMKMT2ANPC1
SCHEMBL14901085 0.82 KDM4E (0.39) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL14901088 0.80 KDM4E (0.40) L3MBTL1KDM4EATMKMT2APLA2G10
SCHEMBL14901084 0.80 CYP1A2 (0.41) L3MBTL1KDM4EATMKMT2ANPC1
SCHEMBL14901087 0.80 KDM4E (0.40) L3MBTL1KDM4EATMKMT2APLA2G10
SCHEMBL24295147 0.75 L3MBTL1 (0.57) L3MBTL1KDM4EATMKMT2AHTR7
SCHEMBL24127584 0.74 L3MBTL1 (0.59) L3MBTL1KDM4EATMKMT2APLA2G10
SCHEMBL25799362 0.74 L3MBTL1 (0.59) L3MBTL1KDM4EATMKMT2APLA2G10
SCHEMBL19075915 0.73 L3MBTL1 (0.57) L3MBTL1KDM4EATMKMT2AHTR7
SCHEMBL19075905 0.73 L3MBTL1 (0.53) L3MBTL1KDM4EATMKMT2AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9051266-B2 Carbazole derivatives and organic light emitting diodes comprising the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-06-09 — — US disclosed
US-9051266-B2 Carbazole derivatives and organic light emitting diodes comprising the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-06-09 — — US disclosed
US-20130105767-A1 CARBAZOLE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODES COMPRISING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-05-02 — — US disclosed
US-20130105767-A1 CARBAZOLE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODES COMPRISING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-05-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130105767-A1 CARBAZOLE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODES COMPRISING THE SAME DRD1, DRD3, DOT1L L3MBTL1 52/4885KDM4E 2187/4885ATM 1479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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