SCHEMBL14901088

SCHEMBL14901088

OC(c1cccc(-n2c3ccccc3c3ccccc32)c1)(c1cccc(-n2c3ccccc3c3ccccc32)c1)c1ccsc1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.40
▸ ATM Q13315 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ KMT2A Q03164 2/20 0.33
▸ PLA2G10 O15496 1/20 0.31
▸ IL1R1 P14778 1/20 0.30
▸ FOLH1 Q04609 1/20 0.30
▸ PPARG P37231 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14901082 0.80 L3MBTL1 (0.44) KDM4EATML3MBTL1KMT2APLA2G10
SCHEMBL14901084 0.76 CYP1A2 (0.41) KDM4EATML3MBTL1KMT2APLA2G10
SCHEMBL14901087 0.76 KDM4E (0.40) KDM4EATML3MBTL1KMT2APLA2G10
SCHEMBL14901085 0.75 KDM4E (0.39) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL14901090 0.75 KDM4E (0.39) KDM4EATML3MBTL1KMT2APPARG
SCHEMBL24127584 0.70 L3MBTL1 (0.59) KDM4EATML3MBTL1KMT2APLA2G10
SCHEMBL25799362 0.70 L3MBTL1 (0.59) KDM4EATML3MBTL1KMT2APLA2G10
SCHEMBL2269282 0.68 KDM4E (0.47) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL29518761 0.68 ATM (0.65) KDM4EATML3MBTL1KMT2AIL1R1
SCHEMBL29598680 0.68 ATM (0.65) KDM4EATML3MBTL1KMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9051266-B2 Carbazole derivatives and organic light emitting diodes comprising the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-06-09 — — US disclosed
US-9051266-B2 Carbazole derivatives and organic light emitting diodes comprising the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-06-09 — — US disclosed
US-20130105767-A1 CARBAZOLE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODES COMPRISING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-05-02 — — US disclosed
US-20130105767-A1 CARBAZOLE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODES COMPRISING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-05-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130105767-A1 CARBAZOLE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODES COMPRISING THE SAME DRD1, DRD3, DOT1L KDM4E 2187/4885ATM 1479/4885L3MBTL1 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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