Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445572 | 1.00 | MAPK1 (0.50) | MAPK1ALDH1A1TSHR | |
| SCHEMBL14901114 | 1.00 | MAPK1 (0.50) | MAPK1ALDH1A1TSHR | |
| SCHEMBL12858723 | 0.83 | MAPK1 (0.60) | MAPK1ALDH1A1 | |
| SCHEMBL18974241 | 0.80 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL6446870 | 0.78 | ALDH1A1 (0.35) | MAPK1ALDH1A1TSHR | |
| SCHEMBL14901099 | 0.76 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL12285564 | 0.76 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL14901100 | 0.76 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL4181754 | 0.74 | MAPK1 (0.56) | MAPK1TSHR | |
| SCHEMBL4189322 | 0.74 | MAPK1 (0.56) | MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130109758-A1 | BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109758-A1 | BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | SHBG, KLK3, HSD17B11 | MAPK1 3831/4885ALDH1A1 179/4885TSHR 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.