SCHEMBL14901641

SCHEMBL14901641

N=Cc1ccc(Pc2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
TP53 P04637 1/20 0.38
CA1 P00915 1/20 0.38
MGLL Q99685 1/20 0.38
MAPT P10636 2/20 0.38
LMNA P02545 1/20 0.38
ALDH1A1 P00352 3/20 0.38
CYP3A4 P08684 3/20 0.37
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KIF11 P52732 1/20 0.35
HDAC2 Q92769 2/20 0.35
MAPK1 P28482 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2606098 0.87 ALDH1A1 (0.50) MMP3BCL2L1TP53CA1MGLL
SCHEMBL5414256 0.82 ALDH1A1 (0.56) MMP3BCL2L1CA1MGLLMAPT
SCHEMBL1304675 0.79 ALDH1A1 (0.53) MMP3BCL2L1CA1MGLLMAPT
SCHEMBL28449419 0.79 ALDH1A1 (0.53) MMP3BCL2L1CA1MGLLMAPT
SCHEMBL25978979 0.78 ASIC1 (0.46) TP53CA1MGLLMAPTLMNA
SCHEMBL25978986 0.78 ASIC1 (0.46) TP53CA1MGLLMAPTLMNA
SCHEMBL25978983 0.78 ASIC1 (0.46) TP53CA1MGLLMAPTLMNA
SCHEMBL25978992 0.78 ASIC1 (0.46) TP53CA1MGLLMAPTLMNA
SCHEMBL25978985 0.78 ASIC1 (0.46) TP53CA1MGLLMAPTLMNA
SCHEMBL25978989 0.78 ASIC1 (0.46) TP53CA1MGLLMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013062043-A1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME 東ソー株式会社 (JP) 2013-05-02 WO disclosed