SCHEMBL14901670

SCHEMBL14901670

N=C/C=C\C=C\n1c2ccccc2c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.37
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
SLC6A2 P23975 1/20 0.32
CYP19A1 P11511 1/20 0.31
POLB P06746 1/20 0.31
BACE1 P56817 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19001746 0.80 GPR3 (0.41) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL13947693 0.73 GPR3 (0.46) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL7193414 0.70 GPR3 (0.48) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL6708485 0.70 GPR3 (0.48) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL6708483 0.70 GPR3 (0.48) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL19823539 0.69 POLB (0.38) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL28445754 0.68 GPR3 (0.41) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL17457910 0.67 HTR6 (0.53) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL31573798 0.67 HTR6 (0.53) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL17457911 0.67 HTR6 (0.53) GPR3CYP1A2CYP2C19KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013062043-A1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME 東ソー株式会社 (JP) 2013-05-02 WO disclosed