Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12074251 | 0.89 | TDO2 (0.34) | TDO2HSP90AA1HSP90AB1CNR1CNR2 | |
| SCHEMBL14904030 | 0.87 | PDE4A (0.33) | TDO2HSP90AA1HSP90AB1CNR1CNR2 | |
| SCHEMBL12074099 | 0.84 | TDO2 (0.36) | TDO2HSP90AA1HSP90AB1TP53MAPT | |
| SCHEMBL12074910 | 0.81 | ACACA (0.37) | MEN1KMT2AATMMAPTPDGFRB | |
| SCHEMBL14904028 | 0.79 | PDCD1 (0.36) | MEN1KMT2AMAPTFYN | |
| SCHEMBL14904029 | 0.75 | PDE4A (0.36) | TDO2HSP90AA1HSP90AB1TP53MAPT | |
| SCHEMBL12074701 | 0.75 | TDO2 (0.37) | TDO2HSP90AA1HSP90AB1RAB9AATM | |
| SCHEMBL12074073 | 0.73 | FYN (0.41) | MEN1RAB9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12074242 | 0.72 | GAK (0.49) | TDO2MEN1KMT2AMAPTPDGFRB | |
| SCHEMBL12074707 | 0.72 | TDO2 (0.43) | TDO2HSP90AA1HSP90AB1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102617-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-08-11 | — | — | US | disclosed |
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | RPS4X, RPS4Y1, MRPL21 | TDO2 4238/4885HSP90AA1 1698/4885HSP90AB1 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.