Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 11/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 11/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 11/20 | 0.54 |
| ▸ | PDE5A | O76074 | 10/20 | 0.54 |
| ▸ | PDE1A | P54750 | 9/20 | 0.54 |
| ▸ | PDE1B | Q01064 | 9/20 | 0.54 |
| ▸ | PDE1C | Q14123 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14903977 | 0.83 | ACACA (0.44) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL14903975 | 0.80 | PDE5A (0.55) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL14903964 | 0.79 | PDE5A (0.49) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL14926983 | 0.74 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL14903968 | 0.72 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL14904013 | 0.71 | PTPN1 (0.39) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL14904027 | 0.70 | PDCD1 (0.39) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL14926985 | 0.70 | PDE5A (0.54) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL129668 | 0.70 | PDE3B (0.48) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL14903963 | 0.69 | PDE5A (0.53) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | RPS4X, RPS4Y1, MRPL21 | PDE4A 1953/4885PDE4B 2010/4885PDE4C 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.