Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 5/20 | 0.54 |
| ▸ | PDE4A | P27815 | 5/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.54 |
| ▸ | PDE1A | P54750 | 4/20 | 0.54 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.54 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.54 |
| ▸ | ACACA | Q13085 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14926991 | 0.83 | HSD17B10 (0.48) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14903963 | 0.81 | PDE5A (0.53) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12070525 | 0.81 | KDM4E (0.50) | ACACAKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL14926983 | 0.78 | PDE4A (0.51) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14903966 | 0.76 | ACACA (0.47) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14903975 | 0.75 | PDE5A (0.55) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12070532 | 0.75 | L3MBTL1 (0.53) | PDE4APDE4BPDE4CPDE4DACACA | |
| SCHEMBL14903964 | 0.73 | PDE5A (0.49) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14926989 | 0.70 | KMT2A (0.42) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14904332 | 0.70 | PDE4A (0.54) | PDE5APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | MRPL21, ARG1, RPP30 | PDE5A 2129/4885PDE4A 2153/4885PDE4B 2021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.