Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.73 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | NCOA3 | Q9Y6Q9 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.65 |
| ▸ | MITF | O75030 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.63 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.60 |
| ▸ | TCF4 | P15884 | 1/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.60 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13446523 | 0.91 | CISD1 (0.70) | FABP4CISD1MAOAMAPTNCOA3 | |
| SCHEMBL12008720 | 0.90 | FABP4 (0.74) | FABP4CISD1MAOAMAPTNCOA3 | |
| SCHEMBL20558643 | 0.89 | PTPN12 (0.65) | FABP4KMT2AADAMTS5MEN1AKR1B1 | |
| SCHEMBL20558641 | 0.89 | PTPN12 (0.65) | FABP4KMT2AADAMTS5MEN1AKR1B1 | |
| SCHEMBL7251139 | 0.87 | TAS2R14 (0.70) | FABP4CISD1MAOAMAPTNCOA3 | |
| SCHEMBL7251137 | 0.87 | TAS2R14 (0.70) | FABP4CISD1MAOAMAPTNCOA3 | |
| SCHEMBL6886610 | 0.87 | FABP4 (0.57) | FABP4CISD1MAOAMAPTNCOA3 | |
| SCHEMBL17779685 | 0.87 | TAS2R14 (0.66) | FABP4CISD1MAOAMAPTNCOA3 | |
| SCHEMBL17225892 | 0.86 | CISD1 (0.64) | FABP4CISD1MAOAMAPTNCOA3 | |
| SCHEMBL12008489 | 0.86 | FABP4 (0.81) | FABP4CISD1MAOAMAPTNCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130109675-A1 | OXAZOLE AND THIAZOLE COMPOUNDS AS BETA-CATENIN MODULATORS AND USES THEREOF | NEW YORK UNIVERSITY | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109675-A1 | OXAZOLE AND THIAZOLE COMPOUNDS AS BETA-CATENIN MODULATORS AND USES THEREOF | CTNNB1, CTNNA1, CTNNBL1 | FABP4 1744/4885CISD1 2618/4885MAOA 3935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.