Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCND2 | P30279 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718165 | 0.75 | TSHR (0.40) | MAPTKMT2ATSHR | |
| SCHEMBL28725043 | 0.75 | ALOX5 (0.42) | MAPTKMT2ATSHRMEN1HTT | |
| SCHEMBL25352818 | 0.74 | MAP2K1 (0.33) | MAPTKMT2ATSHRMEN1 | |
| SCHEMBL3356162 | 0.73 | KMT2A (0.49) | MAPTKMT2ATSHRMEN1 | |
| SCHEMBL15309515 | 0.71 | CYP3A4 (0.36) | MAPTTP53KMT2ATSHRMEN1 | |
| SCHEMBL553835 | 0.71 | GABRP (0.44) | KMT2ATSHRMEN1 | |
| SCHEMBL27860338 | 0.70 | HMGCR (0.37) | CCNE2CCNE1CDK2KMT2AMEN1 | |
| SCHEMBL18989231 | 0.70 | CDC7 (0.36) | MAPTKMT2AMEN1 | |
| SCHEMBL29159076 | 0.70 | POLB (0.39) | CYP4F2CYP4A11MAPTTP53KMT2A | |
| SCHEMBL25351425 | 0.68 | KDM4E (0.47) | MAPTTP53TSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436043-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-05-07 | — | — | US | disclosed |