Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.35 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.34 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1617220 | 0.86 | ENPP2 (0.41) | TSHRENPP2LPAR2ALDH1A1TP53 | |
| SCHEMBL28006286 | 0.81 | ENPP2 (0.44) | TSHRENPP2LPAR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11408483 | 0.79 | PLA2G2C (0.41) | TSHRITPR3ITPR1ALDH1A1CYP3A4 | |
| SCHEMBL28006288 | 0.79 | SMN1; SMN2 (0.55) | TSHRENPP2LPAR2ALDH1A1CYP3A4 | |
| SCHEMBL17488878 | 0.78 | ENPP2 (0.40) | TSHRENPP2LPAR2ALDH1A1TP53 | |
| SCHEMBL28208986 | 0.77 | FABP3 (0.37) | TSHRENPP2LPAR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL27651923 | 0.76 | ALDH1A1 (0.38) | TSHRENPP2LPAR2ALDH1A1TP53 | |
| Ether SCHEMBL20767714 | 0.76 | ENPP2 (0.42) | TSHRENPP2LPAR2ALDH1A1TP53 | |
| SCHEMBL1987367 | 0.73 | — | — | |
| SCHEMBL27736092 | 0.73 | ALDH1A1 (0.53) | TSHRENPP2LPAR2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130110408-A1 | METHODS FOR THE DIAGNOSIS OF DEMENTIA AND OTHER NEUROLOGICAL DISORDERS | PHENOMENOME DISCOVERIES INC. (CA) | 2013-05-02 | — | — | US | disclosed |