Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MMP8 | P22894 | 3/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14906259 | 0.86 | BCHE (0.59) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| SCHEMBL6010174 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| SCHEMBL6010161 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| SCHEMBL30735894 | 0.81 | KDM4E (0.64) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| SCHEMBL14906282 | 0.80 | CSNK1E (0.50) | MMP2MMP1 | |
| Dl-Tryptophan SCHEMBL28198688 | 0.79 | KDM4E (0.67) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| Tryptophan SCHEMBL28198687 | 0.79 | KDM4E (0.67) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| SCHEMBL15044779 | 0.78 | GPR84 (0.45) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| SCHEMBL7766717 | 0.78 | KDM4E (0.55) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| SCHEMBL7766713 | 0.78 | KDM4E (0.55) | SMN1; SMN2KDM4EMAPTAPAF1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013063468-A1 | AMINO ACID DERIVATES FUNCTIONALIZED ON THE N- TERMINAL CAPABLE OF FORMING DRUG INCAPSULATING MICROSPHERES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-02 | — | — | WO | disclosed |