Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29588600 | 1.00 | NOD1 (0.45) | NOD1PLA2G2APLA2G5GRIK1GRIK2 | |
| SCHEMBL20813983 | 0.93 | PLA2G2A (0.41) | NOD1PLA2G2APLA2G5GRIK1GRIK2 | |
| SCHEMBL15044801 | 0.86 | EPHX1 (0.39) | NOD1PLA2G2APLA2G5GRIK1GRIK2 | |
| SCHEMBL11336471 | 0.84 | PLA2G2A (0.36) | NOD1PLA2G2APLA2G5GRIK1GRIK2 | |
| SCHEMBL11336465 | 0.84 | PLA2G2A (0.36) | NOD1PLA2G2APLA2G5GRIK1GRIK2 | |
| SCHEMBL29588653 | 0.83 | NOD1 (0.48) | NOD1GRIK1GRIK2ACE2GPR84 | |
| SCHEMBL30304076 | 0.83 | NOD1 (0.48) | NOD1GRIK1GRIK2ACE2GPR84 | |
| SCHEMBL9839548 | 0.81 | NOD1 (0.47) | NOD1GRIK1GRIK2ACE2GPR84 | |
| SCHEMBL28922591 | 0.81 | NOD1 (0.47) | NOD1GRIK1GRIK2ACE2GPR84 | |
| SCHEMBL30992333 | 0.81 | NOD1 (0.53) | NOD1GRIK1GRIK2ACE2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013063468-A1 | AMINO ACID DERIVATES FUNCTIONALIZED ON THE N- TERMINAL CAPABLE OF FORMING DRUG INCAPSULATING MICROSPHERES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-02 | — | — | WO | disclosed |