Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 9/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22585036 | 0.93 | GPR84 (0.43) | GPR84FFAR1ACE2PPARDMAPT | |
| SCHEMBL15044804 | 0.85 | FAAH (0.39) | GPR84FFAR1MAPT | |
| SCHEMBL14906356 | 0.84 | ACE2 (0.41) | GPR84FFAR1ACE2PPARDMAPT | |
| SCHEMBL6138244 | 0.81 | GPR84 (0.42) | GPR84FFAR1ACE2PPARDMAPT | |
| SCHEMBL6138246 | 0.81 | GPR84 (0.42) | GPR84FFAR1ACE2PPARDMAPT | |
| SCHEMBL28276665 | 0.80 | GPR84 (0.40) | GPR84FFAR1ACE2PPARDMAPT | |
| SCHEMBL20814000 | 0.80 | ACE2 (0.41) | GPR84FFAR1ACE2PPARDMAPT | |
| SCHEMBL15047703 | 0.80 | GPR84 (0.50) | GPR84FFAR1ACE2PPARDMAPT | |
| SCHEMBL31585204 | 0.80 | SMN1; SMN2 (0.40) | GPR84FFAR1ACE2PPARDMAPT | |
| SCHEMBL9839621 | 0.79 | ACE2 (0.46) | GPR84FFAR1ACE2PPARDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013063468-A1 | AMINO ACID DERIVATES FUNCTIONALIZED ON THE N- TERMINAL CAPABLE OF FORMING DRUG INCAPSULATING MICROSPHERES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-02 | — | — | WO | disclosed |