Perflubutane

Perflubutane

SCHEMBL1490719

CC[N+](CC)(CC)CC.FC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
NFKB1 P19838 1/20 0.53
KCNA1 Q09470 1/20 0.53
KDM4E B2RXH2 1/20 0.50
PMP22 Q01453 1/20 0.50
ATM Q13315 1/20 0.50
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrylammonium SCHEMBL1183170 0.97 TSHR (0.50) TSHRNFKB1KCNA1KDM4EPMP22
Tetrylammonium SCHEMBL727741 0.97 TSHR (0.50) TSHRNFKB1KCNA1KDM4EPMP22
Perflenapent SCHEMBL727982 0.97 TSHR (0.50) TSHRNFKB1KCNA1KDM4EPMP22
Perflexane SCHEMBL727759 0.97 TSHR (0.50) TSHRNFKB1KCNA1KDM4EPMP22
Perflutren SCHEMBL729416 0.93 TSHR (0.53) TSHRNFKB1KCNA1KDM4EPMP22
Tetrylammonium SCHEMBL727439 0.86 TSHR (0.61) TSHRNFKB1KCNA1KDM4EPMP22
Tetrylammonium SCHEMBL20237361 0.83 TSHR (0.42) TSHRNFKB1KCNA1KDM4EPMP22
Tetrylammonium SCHEMBL727740 0.82 TSHR (0.67) TSHRNFKB1KCNA1KDM4EPMP22
Tetrylammonium SCHEMBL4581577 0.79 TSHR (0.38) TSHRNFKB1KCNA1KDM4EPMP22
Bromide SCHEMBL22061870 0.75 DNM1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7288579-B2 Method for reducing haze in a fire resistant polycarbonate composition GENERAL ELECTRIC COMPANY (US) 2007-10-30 US claimed
US-20040132865-A1 Method for reducing haze in a fire resistant polycarbonate composition SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2004-07-08 US claimed
US-6730720-B2 BLENDING A FLAME RETARDANT SALT WITH A POLYCARBONATE TO PRODUCE A CONCENTRATE AND THEN BLENDING THE CONCENTRATE WITH A POLYCARBONATE TO FORM A TRANSPARENT POLYCARBONATE BLEND GENERAL ELECTRIC COMPANY 2004-05-04 US claimed
CN-105636997-B Polyorganosiloxane-containing graft copolymer, resin composition, molded body, sliding property improver, and sliding member 三菱化学株式会社 2018-06-19 CN disclosed
EP-2294135-B1 FLAME RETARDANT, OPTICALLY CLEAR THERMOPLASTIC MOLDING COMPOSITION COVESTRO LLC (US) 2017-07-26 EP disclosed
CN-105636997-A Polyorganosiloxane-containing graft copolymer, resin composition, molded body, sliding property improver, and sliding member MITSUBISHI RAYON CO 2016-06-01 CN disclosed
CN-103314054-B Compositions and articles of manufacture comprising siloxanes SABIC INNOVATIVE PLASTICS IP 2015-02-18 CN disclosed
EP-2294135-A2 FLAME RETARDANT, OPTICALLY CLEAR THERMOPLASTIC MOLDING COMPOSITION Bayer MaterialScience LLC (US) 2011-03-16 EP disclosed
WO-2010005486-A2 FLAME RETARDANT, OPTICALLY CLEAR THERMOPLASTIC MOLDING COMPOSITION BAYER MATERIALSCIENCE LLC (US) 2010-01-14 WO disclosed
US-6730725-B2 POLYCARBONATE PRODUCED BY THE MELTING METHOD HAVING EXCELLENT IMPACT RESISTANCE AT LOW TEMPERATURE MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 2004-05-04 US disclosed
US-20020193470-A1 Polycarbonate produced by the melting method having excellent impact resistance at low temperature MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-12-19 US disclosed