Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.73 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NQO2 | P16083 | 2/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14961144 | 0.96 | MTNR1A (0.70) | MTNR1AMTNR1BMEN1CYP1A2BLM | |
| SCHEMBL14961131 | 0.94 | MTNR1A (0.74) | MTNR1AMTNR1BMEN1CYP1A2BLM | |
| SCHEMBL25236273 | 0.84 | MTNR1A (1.00) | MTNR1AMTNR1BMEN1CYP1A2BLM | |
| SCHEMBL27084687 | 0.84 | MTNR1A (0.73) | MTNR1AMTNR1BMEN1CYP1A2BLM | |
| SCHEMBL29112615 | 0.83 | MTNR1A (0.80) | MTNR1AMTNR1BMEN1CYP1A2BLM | |
| SCHEMBL27084955 | 0.83 | MTNR1A (0.74) | MTNR1AMTNR1BMEN1CYP1A2BLM | |
| SCHEMBL14961154 | 0.83 | HTR2A (0.54) | MTNR1AMTNR1BCYP1A2CYP2C19HTR1A | |
| SCHEMBL27084881 | 0.81 | MTNR1A (0.74) | MTNR1AMTNR1BMEN1CYP1A2BLM | |
| SCHEMBL27085140 | 0.81 | MTNR1A (0.74) | MTNR1AMTNR1BMEN1CYP1A2BLM | |
| SCHEMBL27085201 | 0.80 | MTNR1A (0.73) | MTNR1AMTNR1BMEN1CYP1A2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013063492-A1 | NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-05-02 | — | — | WO | disclosed |