Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.78 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.78 |
| ▸ | HTR1A | P08908 | 9/20 | 0.72 |
| ▸ | HTR1D | P28221 | 8/20 | 0.72 |
| ▸ | HTR1B | P28222 | 8/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | BLM | P54132 | 2/20 | 0.70 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.70 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.70 |
| ▸ | MPO | P05164 | 1/20 | 0.70 |
| ▸ | NQO2 | P16083 | 1/20 | 0.70 |
| ▸ | HTR2B | P41595 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907331 | 1.00 | MTNR1A (0.78) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL14907324 | 1.00 | MTNR1A (0.78) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL14907323 | 1.00 | MTNR1A (0.78) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL14907339 | 1.00 | MTNR1A (0.78) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL14907338 | 1.00 | MTNR1A (0.78) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL14907332 | 1.00 | MTNR1A (0.78) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL7020360 | 0.94 | MTNR1A (0.87) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL9327975 | 0.92 | MTNR1A (0.83) | MTNR1AMTNR1BHTR1AHTR1BTDP1 | |
| SCHEMBL31543741 | 0.92 | MTNR1A (0.83) | MTNR1AMTNR1BHTR1AHTR1BTDP1 | |
| SCHEMBL7017649 | 0.90 | MTNR1A (0.87) | MTNR1AMTNR1BHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150306077-A1 | Novel Compositions and Methods for Treating Cancer | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2015-10-29 | — | — | US | disclosed |
| US-20150306077-A1 | Novel Compositions and Methods for Treating Cancer | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2015-10-29 | — | — | US | disclosed |
| US-9073851-B2 | Compositions and methods for treating cancer | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-07-07 | — | — | US | disclosed |
| US-9073851-B2 | Compositions and methods for treating cancer | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-07-07 | — | — | US | disclosed |
| US-20130129812-A1 | NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130129812-A1 | NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-05-23 | — | — | US | disclosed |
| WO-2013063492-A1 | NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150306077-A1 | Novel Compositions and Methods for Treating Cancer | HDGF, HCCS, CCNC | MTNR1A 570/4885MTNR1B 782/4885HTR1A 152/4885 |
| US-20130129812-A1 | NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER | HDGF, HCCS, CCNC | MTNR1A 570/4885MTNR1B 782/4885HTR1A 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.