Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907460 | 0.91 | RARB (0.45) | RARBTHRBALDH1A1CYP3A4TSHR | |
| SCHEMBL14907469 | 0.87 | THRB (0.50) | RARBTHRBS1PR1S1PR3ALDH1A1 | |
| SCHEMBL22451142 | 0.85 | THRB (0.57) | THRBMAPTSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL14907523 | 0.85 | THRB (0.44) | RARBTHRBS1PR1S1PR3ALDH1A1 | |
| SCHEMBL803177 | 0.84 | THRB (0.49) | RARBTHRBS1PR1S1PR3ALDH1A1 | |
| SCHEMBL14907448 | 0.84 | THRB (0.56) | THRBMAPTSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL3437310 | 0.83 | CA12 (0.44) | RARBTHRBMAPTSMN1; SMN2S1PR1 | |
| SCHEMBL17773133 | 0.82 | THRB (0.56) | THRBMAPTSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL12933641 | 0.82 | THRB (0.49) | RARBTHRBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18540273 | 0.82 | RARB (0.42) | RARBTHRBMAPTSMN1; SMN2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9507185-B2 | Switch element comprising a liquid crystalline medium | MERCK PATENT GMBH (DE) | 2016-11-29 | — | — | US | disclosed |
| US-9507185-B2 | Switch element comprising a liquid crystalline medium | MERCK PATENT GMBH (DE) | 2016-11-29 | — | — | US | disclosed |
| US-20140293174-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| US-20140293174-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| WO-2013060406-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2013-05-02 | — | — | WO | disclosed |