Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22451142 | 0.99 | THRB (0.57) | THRBALDH1A1TSHRCYP3A4THRA | |
| SCHEMBL17364495 | 0.95 | THRB (0.53) | THRBALDH1A1TSHRCYP3A4THRA | |
| SCHEMBL14000685 | 0.95 | THRB (0.53) | THRBALDH1A1TSHRCYP3A4THRA | |
| SCHEMBL12090477 | 0.94 | THRB (0.53) | THRBALDH1A1TSHRCYP3A4THRA | |
| SCHEMBL17279039 | 0.94 | THRB (0.51) | THRBALDH1A1TSHRCYP3A4MEN1 | |
| SCHEMBL1072168 | 0.94 | THRB (0.51) | THRBALDH1A1TSHRCYP3A4MEN1 | |
| SCHEMBL13089478 | 0.94 | THRB (0.51) | THRBALDH1A1TSHRCYP3A4MEN1 | |
| SCHEMBL17773133 | 0.93 | THRB (0.56) | THRBALDH1A1TSHRCYP3A4THRA | |
| SCHEMBL17146872 | 0.93 | THRB (0.54) | THRBALDH1A1TSHRCYP3A4THRA | |
| SCHEMBL25501133 | 0.92 | THRB (0.52) | THRBALDH1A1TSHRCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |
| US-9507185-B2 | Switch element comprising a liquid crystalline medium | MERCK PATENT GMBH (DE) | 2016-11-29 | — | — | US | disclosed |
| US-9507185-B2 | Switch element comprising a liquid crystalline medium | MERCK PATENT GMBH (DE) | 2016-11-29 | — | — | US | disclosed |
| US-20140293174-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| US-20140293174-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| WO-2013060406-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2013-05-02 | — | — | WO | disclosed |