Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1490847 | 0.99 | ALDH1A1 (0.36) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL5824061 | 0.89 | ALDH1A1 (0.36) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL1490782 | 0.80 | CYP1A2 (0.36) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL1490846 | 0.80 | CYP1A2 (0.36) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL1491010 | 0.79 | AAK1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL1490912 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL5824055 | 0.76 | ALDH1A1 (0.36) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL1490946 | 0.76 | MET (0.35) | MAPTCYP1A2CYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1490938 | 0.72 | ALDH1A1 (0.35) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL3861813 | 0.69 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897609-B2 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-01 | — | — | US | disclosed |
| US-20070219228-A1 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219228-A1 | Aryl substituted imidazonaphthyridines | IL2, IRF3, EIF2AK2 | ALDH1A1 1178/4885HPGD 449/4885KDM4E 3178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.