⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490575 | 0.91 | BRD4 (0.35) | — | |
| SCHEMBL1490240 | 0.89 | HTR1A (0.41) | — | |
| SCHEMBL1490563 | 0.88 | FAAH (0.37) | — | |
| SCHEMBL1490732 | 0.86 | TLR7 (0.42) | — | |
| SCHEMBL5030364 | 0.81 | MEN1 (0.30) | — | |
| SCHEMBL5030447 | 0.80 | TLR7 (0.33) | — | |
| SCHEMBL1490814 | 0.77 | BRD4 (0.32) | — | |
| SCHEMBL1490694 | 0.77 | HTR1A (0.37) | — | |
| SCHEMBL1490705 | 0.76 | HTR1A (0.38) | — | |
| SCHEMBL4329081 | 0.74 | PDE4A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897767-B2 | Oxime substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-01 | — | — | US | disclosed |
| US-20090042925-A1 | OXIME SUBSTITUTED IMIDAZOQUINOLINES | COLEY PHARMACEUTICAL GROUP, INC. | 2009-02-12 | — | — | US | disclosed |