Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177578 | 0.92 | SMN1; SMN2 (0.70) | L3MBTL1SMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL3995095 | 0.88 | SMN1; SMN2 (0.52) | L3MBTL1SMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL4552863 | 0.87 | ALDH1A1 (0.57) | L3MBTL1SMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL6361446 | 0.85 | GAA (0.73) | L3MBTL1SMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL13753863 | 0.84 | L3MBTL1 (0.63) | L3MBTL1SMN1; SMN2ALDH1A1POLBGAA | |
| SCHEMBL4938777 | 0.83 | GUSB (0.51) | L3MBTL1SMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL14336245 | 0.82 | ALDH1A1 (0.64) | L3MBTL1SMN1; SMN2ALDH1A1POLBGAA | |
| SCHEMBL8386465 | 0.82 | L3MBTL1 (0.61) | L3MBTL1SMN1; SMN2ALDH1A1POLBGAA | |
| SCHEMBL13763531 | 0.82 | L3MBTL1 (0.80) | L3MBTL1SMN1; SMN2ALDH1A1POLBGAA | |
| SCHEMBL4046701 | 0.81 | KMT2A (0.69) | POLBGAAKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897609-B2 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-01 | — | — | US | disclosed |
| US-20070219228-A1 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219228-A1 | Aryl substituted imidazonaphthyridines | IL2, IRF3, EIF2AK2 | L3MBTL1 3174/4885SMN1; SMN2 3309/4885ALDH1A1 1178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.