Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491015 | 0.73 | HDAC1 (0.47) | PTGS2EGFRPTGS1HCAR2MAPT | |
| SCHEMBL28089087 | 0.68 | KDM4E (0.42) | KDM4ECYP2A6EGFRHCAR2MAPT | |
| SCHEMBL2008389 | 0.68 | ATM (0.66) | KDM4ESMYD3CYP2A6ATMCYP11B1 | |
| SCHEMBL17161760 | 0.67 | PTGS2 (0.39) | CYP2A6PTGS2CYP11B1CYP11B2 | |
| SCHEMBL21621638 | 0.67 | CYP2A6 (0.36) | DYRK1ACYP2A6ATMCYP11B1CYP11B2 | |
| SCHEMBL7817677 | 0.67 | HCAR2 (0.59) | DYRK1AKDM4ECYP2A6CYP11B1CYP11B2 | |
| SCHEMBL30777432 | 0.67 | HCAR2 (0.59) | DYRK1AKDM4ECYP2A6CYP11B1CYP11B2 | |
| SCHEMBL19556182 | 0.66 | CYP2C19 (0.66) | ATMMAPTHTTSMN1; SMN2 | |
| SCHEMBL18340498 | 0.65 | CYP11B2 (0.49) | KDM4ECYP11B1CYP11B2HCAR2 | |
| SCHEMBL23021760 | 0.65 | SMN1; SMN2 (0.41) | DYRK1AKDM4ECYP2A6ATMCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897609-B2 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-01 | — | — | US | disclosed |