Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065158 | 1.00 | KDM4E (0.55) | KDM4EALDH1A1AOC3GAASLC6A4 | |
| SCHEMBL5065151 | 1.00 | KDM4E (0.55) | KDM4EALDH1A1AOC3GAASLC6A4 | |
| SCHEMBL20492448 | 0.87 | ALDH1A1 (0.40) | KDM4EALDH1A1AOC3GAASLC6A4 | |
| SCHEMBL7647994 | 0.87 | NPY5R (0.46) | KDM4EALDH1A1AOC3GAASLC6A4 | |
| SCHEMBL20492498 | 0.85 | ALOX5 (0.41) | KDM4EALDH1A1AOC3GAASLC6A4 | |
| SCHEMBL14909184 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1AOC3GAA | |
| SCHEMBL837657 | 0.85 | ACP3 (0.40) | KDM4EALDH1A1AOC3GAANPY5R | |
| SCHEMBL835711 | 0.84 | UGT2B7 (0.49) | AOC3SLC6A4HIF1A | |
| SCHEMBL19459927 | 0.83 | GAA (0.44) | KDM4EALDH1A1AOC3GAASLC6A4 | |
| SCHEMBL19517259 | 0.83 | GAA (0.44) | KDM4EALDH1A1AOC3GAASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-B1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM CORP (JP) | 2018-08-22 | — | — | EP | disclosed |
| US-8895585-B2 | Nicotinamide derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| US-8809371-B2 | — | — | 2014-08-19 | — | — | US | disclosed |
| US-8772320-B2 | — | — | 2014-07-08 | — | — | US | disclosed |
| US-20130116430-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2013-05-09 | — | — | US | disclosed |
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116430-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | SYK, CD38, BTK | KDM4E 2420/4885ALDH1A1 1638/4885AOC3 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.