Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ADK | P55263 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490629 | 0.76 | APP (0.44) | APPALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL17616448 | 0.74 | ALDH1A1 (0.48) | APPACACBALDH1A1TSHRALOX15 | |
| SCHEMBL10300053 | 0.72 | ALDH1A1 (0.65) | APPACACBALDH1A1TSHRALOX15 | |
| SCHEMBL770159 | 0.72 | ALDH1A1 (0.65) | APPACACBALDH1A1TSHRALOX15 | |
| SCHEMBL9241732 | 0.71 | ADK (0.48) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL20025521 | 0.71 | ALDH1A1 (0.44) | APPACACBALDH1A1TSHRALOX15 | |
| SCHEMBL8013623 | 0.68 | ALDH1A1 (0.44) | ALDH1A1TSHRHSD17B10GAAMEN1 | |
| SCHEMBL20001579 | 0.68 | APP (0.44) | APPACACBALDH1A1TSHRALOX15 | |
| SCHEMBL9131675 | 0.67 | CHRM5 (0.47) | ALDH1A1TSHRALOX15HSD17B10GAA | |
| SCHEMBL20025519 | 0.67 | ALDH1A1 (0.39) | APPACACBALDH1A1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2477698-A2 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | Centre National de la Recherche Scientifique (FR) | 2012-07-25 | — | — | EP | disclosed |
| WO-2011033115-A2 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-03-24 | — | — | WO | disclosed |