Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27642271 | 0.82 | CYP3A4 (0.49) | CYP3A4TP53ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL27592748 | 0.81 | CYP3A4 (0.50) | CYP3A4TP53ALDH1A1TSHRMEN1 | |
| SCHEMBL5317084 | 0.81 | L3MBTL1 (0.47) | TP53ALDH1A1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL10520830 | 0.80 | CYP3A4 (0.48) | CYP3A4TP53ALDH1A1TSHRMEN1 | |
| SCHEMBL17980515 | 0.80 | CYP3A4 (0.48) | CYP3A4TP53ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7331938 | 0.79 | CYP3A4 (0.53) | CYP3A4TP53ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL23870906 | 0.78 | CYP3A4 (0.47) | CYP3A4TP53ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10198750 | 0.78 | CYP3A4 (0.56) | CYP3A4TP53ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL13360054 | 0.78 | PPARG (0.48) | ALDH1A1MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL9857800 | 0.74 | ELANE (0.44) | MEN1KMT2AMAPTHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910270-B1 | COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD | NOGRA PHARMA LTD (IE) | 2013-05-08 | — | — | EP | disclosed |