Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957443 | 0.89 | TSHR (0.42) | CA1CA2CA9CA12IDO1 | |
| SCHEMBL8957396 | 0.88 | IDO1 (0.52) | CA1CA2CA9CYP19A1CA12 | |
| SCHEMBL6752122 | 0.86 | IDO1 (0.46) | CA1CA2CA9CA12IDO1 | |
| SCHEMBL17966102 | 0.85 | CA12 (0.46) | CA1CA2CA9TDP1CA12 | |
| SCHEMBL17966112 | 0.85 | CA12 (0.46) | CA1CA2CA9TDP1CA12 | |
| SCHEMBL7591237 | 0.85 | CA12 (0.46) | CA1CA2CA9TDP1CA12 | |
| SCHEMBL600669 | 0.85 | CA12 (0.46) | CA1CA2CA9TDP1CA12 | |
| SCHEMBL5150726 | 0.80 | ACHE (0.42) | CYP19A1NPC1RAB9A | |
| SCHEMBL13738263 | 0.80 | TAAR1 (0.42) | CA1CA2CA9CYP19A1CA12 | |
| SCHEMBL22227479 | 0.80 | CA12 (0.36) | CA1CA2CA9PIN1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109126823-A | Nitrobenzene selective hydrogenation prepares the catalyst and preparation method, application of aniline | 江西理工大学 | 2019-01-04 | — | — | CN | claimed |
| CN-109053453-A | A kind of synthetic method of α-o-nitrophenylethanol | 江苏师范大学 | 2018-12-21 | — | — | CN | claimed |
| CN-107537565-A | Cross linked amphoteric polymeric supported precious metal catalyst and preparation and alcohol method for oxidation | 中国科学院大连化学物理研究所 | 2018-01-05 | — | — | CN | claimed |
| CN-105363394-B | A kind of preparation and application of the magnetic fluorescence molecular engram nanoparticle for detecting nitrobenzene | 济南大学 | 2017-11-07 | — | — | CN | claimed |
| EP-0689435-A1 | USE OF SUBSTITUTED ALKYL NITRATES FOR THE TREATMENT OF PATHOLOGICALLY INCREASED INTRA-OCULAR PRESSURE | BYK NEDERLAND BV (NL) | 1996-01-03 | — | — | EP | claimed |
| WO-1994021248-A1 | USE OF SUBSTITUTED ALKYL NITRATES FOR THE TREATMENT OF PATHOLOGICALLY INCREASED INTRA-OCULAR PRESSURE | BYK NEDERLAND BV (NL) | 1994-09-29 | — | — | WO | claimed |
| WO-2025007135-A9 | CONTROLLED GLYCAN METABOLIC ENGINEERING SYSTEMS AND APPLICATIONS THEREOF | WAYNE STATE UNIVERSITY (US) | 2025-03-27 | — | — | WO | disclosed |
| WO-2025007135-A2 | CONTROLLED GLYCAN METABOLIC ENGINEERING SYSTEMS AND APPLICATIONS THEREOF | WAYNE STATE UNIVERSITY (US) | 2025-01-02 | — | — | WO | disclosed |
| WO-2021109336-A1 | METHOD FOR SIMULTANEOUSLY DETERMINING NITROGEN AND OXYGEN ISOTOPIC COMPOSITION OF NATURAL NITRATE AND NITROGEN AND OXYGEN ISOTOPIC COMPOSITION OF NATURAL NITRITE | 陕西科技大学 | 2021-06-10 | — | — | WO | disclosed |
| US-10724036-B2 | System and method for reversible photo-controlled gene silencing | UNIVERSITY OF ONTARIO INSTITUTE OF TECHNOLOGY (CA) | 2020-07-28 | — | — | US | disclosed |
| CN-105696017-B | A kind of new technique method of iron reduction nitrobenzene | 盐城工学院 | 2019-05-03 | — | — | CN | disclosed |
| CN-106748753-B | The method of ethyl alcohol ethyl acetate coproduction arylamine | 江苏扬农化工集团有限公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-109516945-A | A kind of preparation method of 5- methoxy-Indole | 嘉兴市秀洲区洪合镇中学 | 2019-03-26 | — | — | CN | disclosed |
| US-20060118002-A1 | Organoclay composition containing quat mixtures | SUD-CHEMIE INC. | 2006-06-08 | — | — | US | disclosed |
| EP-1015623-A1 | DRUG DISCOVERY USING MULTIPLE MEMBRANE MIMETIC AFFINITIES | PURDUE RESEARCH FOUNDATION (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999010522-A1 | DRUG DISCOVERY USING MULTIPLE MEMBRANE MIMETIC AFFINITIES | PURDUE RESEARCH FOUNDATION (US) | 1999-03-04 | — | — | WO | disclosed |
| US-5186747-A | Free-flowing dry powder blends of 1,2-propylene carbonate and finely divided amorphous silica | UNITED CATALYSTS INC. (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0506130-A1 | Organophilic clays preactivated with propylene carbonate | United Catalysts Incorporated (US) | 1992-09-30 | — | — | EP | disclosed |
| US-5049694-A | Cardiovascular disorders | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-09-17 | — | — | US | disclosed |
| EP-0359335-A2 | Pharmaceutical composition having relaxing activity which contains a nitrate ester as active substance | CEDONA PHARMACEUTICALS B.V. (NL) | 1990-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10724036-B2 | System and method for reversible photo-controlled gene silencing | RTCB, CRY1, NSUN3 | CA1 3801/4885CA2 3885/4885CA9 2871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.