SCHEMBL14913974

SCHEMBL14913974

C#C[C@]1(n2ccc(=O)[nH]c2=O)C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 13/20 0.57
P2RY2 P41231 11/20 0.52
P2RY4 P51582 7/20 0.52
POLA1 P09884 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25340327 0.90 P2RY6 (0.55) P2RY6P2RY2P2RY4POLA1
SCHEMBL1129337 0.85 P2RY6 (0.60) P2RY6P2RY2P2RY4POLA1
SCHEMBL150274 0.84 P2RY6 (0.59) P2RY6P2RY2P2RY4POLA1
SCHEMBL7745802 0.84 P2RY6 (0.59) P2RY6P2RY2P2RY4POLA1
SCHEMBL26676224 0.84 P2RY6 (0.59) P2RY6P2RY2P2RY4POLA1
SCHEMBL8441087 0.84 P2RY6 (0.59) P2RY6P2RY2P2RY4POLA1
SCHEMBL30225473 0.84 P2RY6 (0.53) P2RY6P2RY2P2RY4POLA1
SCHEMBL28293726 0.84 P2RY6 (0.58) P2RY6P2RY2P2RY4POLA1
SCHEMBL8441389 0.83 P2RY6 (0.56) P2RY6P2RY2P2RY4POLA1
SCHEMBL1129233 0.83 P2RY6 (0.62) P2RY6P2RY2P2RY4POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10125162-B2 Methods for the development of vaccines based on oligosaccharide-oligonucleotide conjugates BRANDEIS UNIVERSITY (US) 2018-11-13 US disclosed
US-20160051690-A1 METHODS FOR THE DEVELOPMENT OF VACCINES BASED ON OLIGOSACCHARIDE-OLIGONUCLEOTIDE CONJUGATES UNIV BRANDEIS (US) 2016-02-25 US disclosed
US-9080169-B2 Methods for the development of vaccines based on oligosaccharide-oligonucleotide conjugates BRANDEIS UNIVERSITY (US) 2015-07-14 US disclosed
US-20130116417-A1 Methods for the Development of Vaccines Based on Oligosaccharide-Oligonucleotide Conjugates BRANDEIS UNIVERSITY (US) 2013-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10125162-B2 Methods for the development of vaccines based on oligosaccharide-oligonucleotide conjugates DDOST, STT3A, STT3B P2RY6 4582/4885P2RY2 4792/4885P2RY4 4621/4885
US-20130116417-A1 Methods for the Development of Vaccines Based on Oligosaccharide-Oligonucleotide Conjugates DDOST, STT3A, STT3B P2RY6 4527/4885P2RY2 4785/4885P2RY4 4616/4885
US-20160051690-A1 METHODS FOR THE DEVELOPMENT OF VACCINES BASED ON OLIGOSACCHARIDE-OLIGONUCLEOTIDE CONJUGATES DDOST, STT3A, STT3B P2RY6 4582/4885P2RY2 4792/4885P2RY4 4621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.