Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.70 |
| ▸ | CTSS | P25774 | 4/20 | 0.70 |
| ▸ | MME | P08473 | 3/20 | 0.61 |
| ▸ | ECE1 | P42892 | 2/20 | 0.61 |
| ▸ | CTSK | P43235 | 4/20 | 0.58 |
| ▸ | CTSB | P07858 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6389671 | 1.00 | CTSL (0.70) | CTSLCTSSMMEECE1CTSK | |
| SCHEMBL1491409 | 1.00 | CTSL (0.70) | CTSLCTSSMMEECE1CTSK | |
| SCHEMBL320302 | 1.00 | CTSL (0.70) | CTSLCTSSMMEECE1CTSK | |
| SCHEMBL6389667 | 1.00 | CTSL (0.70) | CTSLCTSSMMEECE1CTSK | |
| SCHEMBL1285941 | 1.00 | CTSL (0.70) | CTSLCTSSMMEECE1CTSK | |
| SCHEMBL10663359 | 1.00 | CTSL (0.70) | CTSLCTSSMMEECE1CTSK | |
| SCHEMBL1491412 | 1.00 | CTSL (0.70) | CTSLCTSSMMEECE1CTSK | |
| SCHEMBL14561285 | 1.00 | CTSL (0.70) | CTSLCTSSMMEECE1CTSK | |
| SCHEMBL4754315 | 0.91 | CTSL (0.63) | CTSLCTSSMMEECE1CTSK | |
| SCHEMBL4754230 | 0.91 | CTSL (0.63) | CTSLCTSSMMEECE1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1039886-A4 | HIV/FIV PROTEASE INHIBITORS HAVING A SMALL P3 RESIDUE | SCRIPPS RESEARCH INST (US) | 2001-05-16 | — | — | EP | claimed |
| EP-1039886-A1 | HIV/FIV PROTEASE INHIBITORS HAVING A SMALL P3 RESIDUE | The Cripps Research Institute (US) | 2000-10-04 | — | — | EP | claimed |
| WO-1999029311-A1 | HIV/FIV PROTEASE INHIBITORS HAVING A SMALL P3 RESIDUE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-06-17 | — | — | WO | claimed |
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | disclosed |
| EP-3658569-B1 | PROCESS AND INTERMEDIATES FOR SYNTHESIS OF PEPTIDE COMPOUNDS | NAUREX INC (US) | 2024-01-31 | — | — | EP | disclosed |
| WO-2023239906-A2 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023044171-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-03-23 | — | — | WO | disclosed |
| US-20230000813-A1 | COMPOUND FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE | INTERVET INC. (US) | 2023-01-05 | — | — | US | disclosed |
| CN-115053184-A | Composition for forming EUV resist underlayer film | 日产化学株式会社 | 2022-09-13 | — | — | CN | disclosed |
| CN-109661398-B | Spiro-lactam and di-spiro-lactam NMDA receptor modulators and uses thereof | 阿普廷伊克斯股份有限公司 | 2022-07-05 | — | — | CN | disclosed |
| US-20220112239-A1 | PROCESS AND INTERMEDIATES FOR SYNTHESIS OF PEPTIDE COMPOUNDS | INNOVIVA TRC HOLDINGS LLC | 2022-04-14 | — | — | US | disclosed |
| EP-1081137-A1 | Selective inhibitors of aggrecanase in osteoarthritis treatment | Pfizer Products Inc. (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| US-4720484-A | Peptide compounds having a nitrogenous polycyclic structure | ADIR S.A.R.L. (FR) | 1988-01-19 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |
| EP-0190058-A1 | Peptide derivatives with a polycyclic nitrogen structure, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1986-08-06 | — | — | EP | disclosed |
| US-4452890-A | Method of producing L-threonine by fermentation | AJINOMOTO COMPANY INCORPORATED (JP) | 1984-06-05 | — | — | US | disclosed |
| EP-0066129-A2 | Method for producing L-threonine by fermentation | AJINOMOTO CO., INC. (JP) | 1982-12-08 | — | — | EP | disclosed |
| US-3932489-A | Process for t-butylating hydroxy- or thiol-substituted amino acids | ELI LILLY AND COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220112239-A1 | PROCESS AND INTERMEDIATES FOR SYNTHESIS OF PEPTIDE COMPOUNDS | PEPD, VIP, IAPP | CTSL 46/4885CTSS 1177/4885MME 517/4885 |
| US-20230000813-A1 | COMPOUND FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE | PIGS, BTD, BRD1 | CTSL 2717/4885CTSS 1568/4885MME 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.