SCHEMBL1491546

SCHEMBL1491546

N[C@@H](Cc1ccccc1)C(=O)OC1CCCC1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.64
ALPI P09923 1/20 0.53
PKM P14618 1/20 0.53
PTGS1 P23219 1/20 0.53
XIAP P98170 1/20 0.53
SLC7A5 Q01650 1/20 0.53
DPP4 P27487 3/20 0.47
DPP8 Q6V1X1 2/20 0.47
DPP9 Q86TI2 2/20 0.47
DPP7 Q9UHL4 2/20 0.47
FAP Q12884 1/20 0.47
SLC15A1 P46059 2/20 0.46
HDAC8 Q9BY41 2/20 0.46
LTA4H P09960 1/20 0.44
F2 P00734 2/20 0.44
PRSS1 P07477 2/20 0.44
CTSC P53634 1/20 0.43
ACE P12821 1/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7114295 1.00 TYR (0.64) TYRALPIPKMPTGS1XIAP
SCHEMBL6803149 0.98 TYR (0.62) TYRALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL17707256 0.98 TYR (0.62) TYRALPIPKMPTGS1XIAP
SCHEMBL25769168 0.98 TYR (0.62) TYRALPIPKMPTGS1XIAP
SCHEMBL23643091 0.98 TYR (0.62) TYRALPIPKMPTGS1XIAP
SCHEMBL23642931 0.98 TYR (0.62) TYRALPIPKMPTGS1XIAP
SCHEMBL7782897 0.98 TYR (0.62) TYRALPIPKMPTGS1XIAP
SCHEMBL22375034 0.98 TYR (0.62) TYRALPIPKMPTGS1XIAP
SCHEMBL22375169 0.98 TYR (0.62) TYRALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL27841329 0.97 TYR (0.61) TYRALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3015488-B1 PRODUCTION METHOD FOR POLYAMINO ACID TAKEDA PHARMACEUTICALS CO (JP) 2024-03-06 EP disclosed
EP-2013175-B9 p38 MAP KINASE INHIBITORS MACROPHAGE PHARMA LTD (GB) 2020-11-11 EP disclosed
EP-2013175-B9 p38 MAP KINASE INHIBITORS MACROPHAGE PHARMA LTD (GB) 2020-11-11 EP disclosed
US-10336864-B2 Production method for poly(amino acid) TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-07-02 US disclosed
US-20180044472-A1 PRODUCTION METHOD FOR POLY(AMINO ACID) TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-02-15 US disclosed
US-9815938-B2 Production method for poly(amino acid) TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-11-14 US disclosed
EP-2013175-B1 p38 MAP KINASE INHIBITORS CHROMA THERAPEUTICS LTD (GB) 2016-11-09 EP disclosed
EP-2013175-B1 p38 MAP KINASE INHIBITORS CHROMA THERAPEUTICS LTD (GB) 2016-11-09 EP disclosed
US-20160177032-A1 PRODUCTION METHOD FOR POLY(AMINO ACID) TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-06-23 US disclosed
EP-3015488-A1 PRODUCTION METHOD FOR POLYAMINO ACID Takeda Pharmaceutical Company Limited (JP) 2016-05-04 EP disclosed
EP-1146868-A1 ANTI-INFLAMMATORY AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2001-10-24 EP disclosed
EP-1140058-A1 N-FORMYL HYDROXYLAMINE DERIVATIVES AS ANTIBACTERIAL AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2001-10-10 EP disclosed
US-6169075-B1 ANTITUMOR AGENT INHIBITING THE PROLIFERATION OF A RANGE OF RAPIDLY DIVIDING TUMOUR CELLS LIKE MELANOMA AND/OR LYMPHOMA CELLS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2001-01-02 US disclosed
EP-1054861-A1 CYTOSTATIC AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2000-11-29 EP disclosed
WO-2000043001-A1 ANTI-INFLAMMATORY AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2000-07-27 WO disclosed
WO-2000035440-A1 N-FORMYL HYDROXYLAMINE DERIVATIVES AS ANTIBACTERIAL AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2000-06-22 WO disclosed
CN-1230175-A Cytostatic hydroximic acid derivatives BRITISH BIOTECH PHARM (GB) 1999-09-29 CN disclosed
WO-1999041232-A1 CYTOSTATIC AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1999-08-19 WO disclosed
EP-0925278-A1 CYTOSTATIC HYDROXAMIC ACID DERIVATIVES BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1999-06-30 EP disclosed
WO-1998011063-A1 CYTOSTATIC HYDROXAMIC ACID DERIVATIVES BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1998-03-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044472-A1 PRODUCTION METHOD FOR POLY(AMINO ACID) PGA5, ENPEP, PARG TYR 101/4885ALPI 1763/4885PKM 634/4885
US-10336864-B2 Production method for poly(amino acid) PGA5, ENPEP, PARG TYR 101/4885ALPI 1763/4885PKM 634/4885
US-20160177032-A1 PRODUCTION METHOD FOR POLY(AMINO ACID) PGA5, ENPEP, PARG TYR 101/4885ALPI 1763/4885PKM 634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.