Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360366 | 0.81 | NAPRT (0.50) | MAPTGAATSHRALDH1A1TP53 | |
| SCHEMBL27558551 | 0.81 | TSHR (0.48) | MAPTGAATSHRALDH1A1TP53 | |
| SCHEMBL8863134 | 0.81 | TSHR (0.48) | MAPTGAATSHRALDH1A1TP53 | |
| SCHEMBL28080823 | 0.78 | L3MBTL1 (0.44) | MAPTGAAGFERTSHRALDH1A1 | |
| SCHEMBL27807620 | 0.77 | ALDH1A1 (0.52) | MAPTGAATSHRALDH1A1TP53 | |
| SCHEMBL3271953 | 0.77 | TSHR (0.44) | GAATSHRALDH1A1TP53KMT2A | |
| SCHEMBL4766156 | 0.77 | NAPRT (0.52) | MAPTGAATSHRALDH1A1TP53 | |
| SCHEMBL11685657 | 0.77 | KMT2A (0.44) | MAPTGAATSHRALDH1A1TP53 | |
| SCHEMBL11038625 | 0.76 | ALDH1A1 (0.43) | MAPTGAATSHRALDH1A1TP53 | |
| SCHEMBL28812358 | 0.76 | NAPRT (0.50) | MAPTGAATSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109310060-A | For the composition of Weeds distribution, external member and method | 维德奥特有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-109265400-A | Arginine methyltransferase inhibitor and application thereof | EPIZYME股份有限公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-108884054-A | For treating the compound of proliferative diseases | 儿童医学中心公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-105339351-B | Arginine methyltransferase inhibitors and uses thereof | EPIZYME股份有限公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-108623743-A | The method of big gas ammonia is reduced with multi-anion copolymer and containing the seed products of multi-anion copolymer | 沃戴申生命科学有限责任公司 | 2018-10-09 | — | — | CN | disclosed |
| CN-108472617-A | Include the microcapsules of polyester-urethane shell and hydrophilic nuclear material | 巴斯夫欧洲公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-108472616-A | Include the microcapsules of polyester-urethane shell and hydrophobic nuclear material | 巴斯夫欧洲公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-105873966-B | Fertilizer with polyanionic polymers and method for applying polyanionic polymers to plants | 沃戴申生命科学有限责任公司 | 2018-05-01 | — | — | CN | disclosed |
| CN-105849142-B | Acroleic acid polyurethane composite resin particle | 关西涂料株式会社 | 2018-03-23 | — | — | CN | disclosed |
| CN-107568214-A | A kind of pesticidal solid Nanodispersion and preparation method thereof | 中国农业科学院农业环境与可持续发展研究所 | 2018-01-12 | — | — | CN | disclosed |
| EP-1879895-B1 | ENZYME INHIBITORS | CHROMA THERAPEUTICS LTD (GB) | 2011-06-08 | — | — | EP | disclosed |
| US-7939666-B2 | Enzyme inhibitors | CHROMA THERAPEUTICS LTD. (GB) | 2011-05-10 | — | — | US | disclosed |
| EP-2301939-A1 | Enzyme inhibitors | Chroma Therapeutics Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| US-20090291978-A1 | Enzyme Inhibitors | CHROMA THERAPEUTICS LTD. (GB) | 2009-11-26 | — | — | US | disclosed |
| CN-101133060-A | Enzyme inhibitors | CHROMA THERAPEUTICS LTD (GB) | 2008-02-27 | — | — | CN | disclosed |
| EP-1879895-A1 | ENZYME INHIBITORS | Chroma Therapeutics Limited (GB) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117549-A1 | ENZYME INHIBITORS | CHROMA THERAPEUTICS LTD (GB) | 2006-11-09 | — | — | WO | disclosed |
| CN-1250549-C | Indole derivatives and their use as 5-ht2b and 5-ht2c receptor ligands | HOFFMANN LA ROCHE (CH) | 2006-04-12 | — | — | CN | disclosed |
| CN-1483034-A | Indole derivatives and their use as 5-ht2b and 5-ht2c receptor ligands | - | 2004-03-17 | — | — | CN | disclosed |
| US-3979202-A | Meta-bifunctional benzenes and herbicidal compositions | MONSANTO COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291978-A1 | Enzyme Inhibitors | HAT1, NR2E1, NR2C2 | MAPT 4873/4885GAA 3209/4885GFER 2536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.