SCHEMBL14916657

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2172826	0.93	EPHX2 (0.51)	EPHX2EPHX1GALR2GALR1SYK
	SCHEMBL12953404	0.92	EPHX2 (0.56)	EPHX2EPHX1GALR2GALR1SYK
	SCHEMBL12953129	0.90	EPHX2 (0.58)	EPHX2EPHX1GALR2GALR1SYK
	SCHEMBL2093841	0.85	GALR2 (0.46)	EPHX2EPHX1GALR2GALR1SYK
	SCHEMBL5536264	0.85	EPHX1 (0.64)	EPHX2EPHX1GALR2GALR1SYK
	Hydrochloric Acid SCHEMBL411544	0.83	EPHX1 (0.63)	EPHX2EPHX1GALR2GALR1SYK
	SCHEMBL15434152	0.81	EPHX2 (0.50)	EPHX2EPHX1GALR2GALR1SYK
	SCHEMBL15434091	0.81	EPHX2 (0.50)	EPHX2EPHX1GALR2GALR1SYK
	SCHEMBL12953406	0.81	EPHX2 (0.50)	EPHX2EPHX1GALR2GALR1SYK
	SCHEMBL14917221	0.80	GALR2 (0.54)	EPHX2GALR2GALR1ROCK2CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.