Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | GALR2 | O43603 | 1/20 | 0.48 |
| ▸ | GALR1 | P47211 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 5/20 | 0.47 |
| ▸ | AADAC | P22760 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14916657 | 0.93 | EPHX2 (0.56) | EPHX2EPHX1MAPTSYKGALR2 | |
| SCHEMBL2093841 | 0.88 | GALR2 (0.46) | EPHX2EPHX1MAPTSYKGALR2 | |
| SCHEMBL5536264 | 0.88 | EPHX1 (0.64) | EPHX2EPHX1MAPTSYKGALR2 | |
| SCHEMBL12953404 | 0.88 | EPHX2 (0.56) | EPHX2EPHX1MAPTSYKGALR2 | |
| SCHEMBL15434152 | 0.87 | EPHX2 (0.50) | EPHX2EPHX1MAPTSYKGALR2 | |
| SCHEMBL12953406 | 0.87 | EPHX2 (0.50) | EPHX2EPHX1MAPTSYKGALR2 | |
| SCHEMBL15434091 | 0.87 | EPHX2 (0.50) | EPHX2EPHX1MAPTSYKGALR2 | |
| Hydrochloric Acid SCHEMBL411544 | 0.87 | EPHX1 (0.63) | EPHX2EPHX1MAPTSYKGALR2 | |
| SCHEMBL12953129 | 0.87 | EPHX2 (0.58) | EPHX2EPHX1MAPTSYKGALR2 | |
| SCHEMBL12953553 | 0.85 | PIM1 (0.53) | EPHX2EPHX1SYKGALR2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346820-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | Shionogi & Co., Ltd. (JP) | 2011-07-27 | — | — | EP | disclosed |
| WO-2009151152-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-12-17 | — | — | WO | disclosed |