Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17414856 | 0.91 | CA2 (0.41) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL17092507 | 0.85 | GPR84 (0.45) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL27449380 | 0.84 | GPR84 (0.46) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL30633871 | 0.83 | SPHK1 (0.53) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL5703592 | 0.83 | GPR84 (0.63) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL7080657 | 0.83 | GPR84 (0.63) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL7083858 | 0.83 | GPR84 (0.63) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL7076752 | 0.83 | GPR84 (0.63) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL3629168 | 0.83 | GPR84 (0.63) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL7083861 | 0.83 | GPR84 (0.63) | GPR84SPHK1FFAR1CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10590363-B2 | Ashless-friction modifiers for lubricating compositions | THE LUBRIZOL CORPORATION | 2020-03-17 | — | — | US | disclosed |
| EP-2773730-B1 | ASHLESS FRICTION MODIFIERS FOR LUBRICATING COMPOSITIONS | LUBRIZOL CORP (US) | 2019-02-13 | — | — | EP | disclosed |
| US-20140303054-A1 | ASHLESS-FRICTION MODIFIERS FOR LUBRICATING COMPOSITIONS | THE LUBRIZOL CORPORATION | 2014-10-09 | — | — | US | disclosed |
| EP-2773730-A1 | ASHLESS FRICTION MODIFIERS FOR LUBRICATING COMPOSITIONS | The Lubrizol Corporation (US) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013066585-A1 | ASHLESS FRICTION MODIFIERS FOR LUBRICATING COMPOSITIONS | THE LUBRIZOL CORPORATION (US) | 2013-05-10 | — | — | WO | disclosed |