⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107 | 0.83 | KDM4E (0.71) | — | |
| SCHEMBL1446623 | 0.82 | — | — | |
| SCHEMBL27890220 | 0.82 | KDM4E (0.44) | — | |
| SCHEMBL1499658 | 0.80 | — | — | |
| SCHEMBL10560389 | 0.79 | — | — | |
| SCHEMBL1499634 | 0.78 | KDM4E (0.80) | — | |
| SCHEMBL1499646 | 0.78 | KDM4E (0.80) | — | |
| SCHEMBL860791 | 0.78 | KDM4E (0.94) | — | |
| SCHEMBL1900471 | 0.78 | KDM4E (0.82) | — | |
| SCHEMBL3921378 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 612 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218014-A1 | SYNTHESIS OF A CYCLIC PEPTIDE | JANSSEN PHARMACEUTICA NV (BE) | 2024-07-04 | — | — | US | claimed |
| WO-2024110477-A2 | SYNTHESIS OF A CYCLIC PEPTIDE | JANSSEN PHARMACEUTICA NV (BE) | 2024-05-30 | — | — | WO | claimed |
| CN-118063554-A | Peptide inhibitors of interleukin-23 receptor and their use for the treatment of inflammatory diseases | 詹森生物科技公司 | 2024-05-24 | — | — | CN | claimed |
| CN-118027153-A | Peptide inhibitors of interleukin-23 receptor and their use for the treatment of inflammatory diseases | 詹森生物科技公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118005736-A | Peptide inhibitors of interleukin-23 receptor and their use for the treatment of inflammatory diseases | 詹森生物科技公司 | 2024-05-10 | — | — | CN | claimed |
| CN-118005737-A | Peptide inhibitors of interleukin-23 receptor and their use for the treatment of inflammatory diseases | 詹森生物科技公司 | 2024-05-10 | — | — | CN | claimed |
| US-20240150405-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES | JANSSEN BIOTECH INC (US) | 2024-05-09 | — | — | US | claimed |
| CN-116082455-A | Peptide inhibitors of interleukin-23 receptor and their use for the treatment of inflammatory diseases | 领导医疗有限公司 | 2023-05-09 | — | — | CN | claimed |
| US-20230129095-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES | PROTAGONIST THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | US | claimed |
| CN-115298196-A | Peptide inhibitors of the interleukin-23 receptor and their use for the treatment of inflammatory diseases | 詹森生物科技公司 | 2022-11-04 | — | — | CN | claimed |
| WO-1992007870-A1 | PLATELET AGGREGATION INHIBITORS | GENENTECH, INC. (US) | 1992-05-14 | — | — | WO | claimed |
| EP-0482080-A1 | SMALL CYCLIC PLATELET AGGREGATION INHIBITORS. | GENENTECH INC (US) | 1992-04-29 | — | — | EP | claimed |
| WO-1991004247-A1 | CHIMERIC AMINO ACIDS AND PEPTIDES CONTAINING THESE ANALOGUES | GENENTECH, INC. (US) | 1991-04-04 | — | — | WO | claimed |
| WO-1991001331-A1 | SMALL CYCLIC PLATELET AGGREGATION INHIBITORS | GENENTECH, INC. (US) | 1991-02-07 | — | — | WO | claimed |
| US-4749688-A | Use of neutral metalloendopeptidase inhibitors in the treatment of hypertension | SCHERING CORPORATION (US) | 1988-06-07 | — | — | US | claimed |
| EP-0254032-A2 | Neutral metalloendopeptidase inhibitors in the treatment of hypertension | SCHERING CORPORATION (US) | 1988-01-27 | — | — | EP | claimed |
| US-4680392-A | Substituted caprolactam derivatives as antihypertensives | MERCK & CO., INC. (US) | 1987-07-14 | — | — | US | claimed |
| EP-0227818-A1 | ANTIGLAUCOMA COMPOSITIONS. | SCHERING CORP (US) | 1987-07-08 | — | — | EP | claimed |
| WO-1987000055-A1 | ANTIGLAUCOMA COMPOSITIONS | SCHERING CORPORATION (US) | 1987-01-15 | — | — | WO | claimed |
| US-4587050-A | Substituted enantholactam derivatives as antihypertensives | MERCK & CO., INC. (US) | 1986-05-06 | — | — | US | claimed |