Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918539 | 1.00 | L3MBTL1 (0.56) | L3MBTL1HDAC1HDAC8HDAC2HDAC3 | |
| SCHEMBL14918439 | 1.00 | L3MBTL1 (0.56) | L3MBTL1HDAC1HDAC8HDAC2HDAC3 | |
| SCHEMBL14919184 | 0.99 | L3MBTL1 (0.57) | L3MBTL1HDAC1HDAC8HDAC2HDAC3 | |
| SCHEMBL14919092 | 0.96 | L3MBTL1 (0.55) | L3MBTL1HDAC1HDAC8HDAC2HDAC3 | |
| SCHEMBL14918925 | 0.91 | MAPT (0.59) | L3MBTL1HDAC1HDAC8HDAC2HDAC3 | |
| SCHEMBL14918725 | 0.88 | MAPT (0.52) | L3MBTL1HDAC1HDAC8HDAC2HDAC3 | |
| SCHEMBL14918935 | 0.88 | MAPT (0.52) | L3MBTL1HDAC1HDAC8HDAC2HDAC3 | |
| SCHEMBL14918847 | 0.88 | MAPT (0.52) | L3MBTL1HDAC1HDAC8HDAC2HDAC3 | |
| SCHEMBL14918334 | 0.87 | HDAC1 (0.52) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL14918820 | 0.87 | HDAC1 (0.52) | HDAC1HDAC8HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066836-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |