Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14919184 | 0.97 | L3MBTL1 (0.57) | L3MBTL1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14918545 | 0.96 | L3MBTL1 (0.56) | L3MBTL1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14918539 | 0.96 | L3MBTL1 (0.56) | L3MBTL1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14918439 | 0.96 | L3MBTL1 (0.56) | L3MBTL1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14918925 | 0.93 | MAPT (0.59) | L3MBTL1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14918382 | 0.88 | MAPT (0.54) | L3MBTL1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14918878 | 0.86 | HDAC6 (0.48) | L3MBTL1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14918418 | 0.85 | RAB9A (0.46) | L3MBTL1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14918887 | 0.85 | MAPT (0.53) | L3MBTL1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14917853 | 0.84 | MAPT (0.53) | L3MBTL1MAPTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066836-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | claimed |
| WO-2013066836-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |