Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 11/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918661 | 1.00 | HDAC4 (0.38) | HDAC4HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL14918912 | 1.00 | HDAC4 (0.38) | HDAC4HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL14918419 | 0.99 | HDAC4 (0.38) | HDAC4HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL14918808 | 0.96 | HDAC4 (0.39) | HDAC4HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL14918729 | 0.91 | HDAC4 (0.40) | HDAC4HDAC6HDAC1 | |
| SCHEMBL14918903 | 0.86 | HDAC1 (0.55) | HDAC4HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL14918844 | 0.86 | HDAC1 (0.55) | HDAC4HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL14918855 | 0.86 | HDAC1 (0.55) | HDAC4HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL14918554 | 0.85 | HDAC1 (0.53) | HDAC4HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL14918655 | 0.84 | HDAC1 (0.43) | HDAC4HDAC6HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066836-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | claimed |
| WO-2013066836-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |