Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.54 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918849 | 0.98 | TBXAS1 (0.51) | TBXAS1TERTALOX15HIF1AEPAS1 | |
| SCHEMBL28056965 | 0.93 | TBXAS1 (0.49) | TBXAS1TERTALOX15TAAR1NAMPT | |
| Hydrochloric Acid SCHEMBL28986374 | 0.91 | TBXAS1 (0.50) | TBXAS1TERTALOX15TAAR1NAMPT | |
| SCHEMBL1003186 | 0.85 | — | — | |
| SCHEMBL28062565 | 0.84 | TBXAS1 (0.69) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL503743 | 0.84 | TBXAS1 (0.69) | TBXAS1TERTALOX15TAAR1FDPS | |
| Hydrochloric Acid SCHEMBL30509739 | 0.83 | TERT (0.46) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL3431746 | 0.82 | TBXAS1 (0.66) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL9834132 | 0.82 | TBXAS1 (0.58) | TBXAS1TERTALOX15TAAR1NAMPT | |
| SCHEMBL9777191 | 0.78 | TBXAS1 (0.60) | TBXAS1TERTALOX15TAAR1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066832-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | claimed |
| WO-2013066832-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |