Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 4/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3701345 | 0.92 | NSD2 (0.72) | NSD2ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL4470111 | 0.91 | NSD2 (0.71) | NSD2ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL4441217 | 0.91 | NSD2 (1.00) | NSD2ALDH1A1KDM4ECYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL4446911 | 0.90 | NSD2 (1.00) | NSD2ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL3693790 | 0.87 | NSD2 (0.70) | NSD2ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL11686439 | 0.86 | NSD2 (0.86) | NSD2ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL4455276 | 0.84 | NSD2 (0.62) | NSD2ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL8624405 | 0.83 | NSD2 (0.60) | NSD2ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL15915771 | 0.81 | RECQL (0.59) | NSD2ALDH1A1SMN1; SMN2HTTNPSR1 | |
| SCHEMBL411161 | 0.81 | SFRP1 (0.66) | NSD2ALDH1A1TDP1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066469-A2 | KINASE INHIBITORS CAPABLE OF INCREASING THE SENSITIVITY OF BACTERIAL PATHOGENS TO B-LACTAM ANTIBIOTICS | SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2013-05-10 | — | — | WO | disclosed |