Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL14919922

N.N[C@@H](Cc1cccc(O)c1)C(=O)O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 1/20 0.79
SLC7A5 Q01650 7/20 0.65
PTGS1 P23219 2/20 0.65
ALPI P09923 1/20 0.65
PKM P14618 1/20 0.65
XIAP P98170 1/20 0.65
KDM4E B2RXH2 1/20 0.60
USP2 O75604 1/20 0.60
EGFR P00533 1/20 0.60
LCK P06239 1/20 0.60
FYN P06241 1/20 0.60
ADORA3 P0DMS8 1/20 0.60
ALOX15 P16050 1/20 0.60
HTR2A P28223 1/20 0.60
PTGS2 P35354 1/20 0.60
RECQL P46063 1/20 0.60
HIF1A Q16665 1/20 0.60
HSD17B10 Q99714 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
NOS3 P29474 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13537526 0.98 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL22721343 0.98 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL31453795 0.98 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL29430938 0.98 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL458080 0.98 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL147042 0.98 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL4356402 0.98 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
Hydrochloric Acid SCHEMBL6491317 0.97 GRIA2 (0.79) GRIA2SLC7A5PTGS1ALPIPKM
Hydrochloric Acid SCHEMBL6491326 0.97 GRIA2 (0.79) GRIA2SLC7A5PTGS1ALPIPKM
Hydrochloric Acid SCHEMBL6491324 0.97 GRIA2 (0.79) GRIA2SLC7A5PTGS1ALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2773752-A1 TRANSGENIC PLANTS RESISTANT TO NON-PROTEIN AMINO ACIDS Yeda Research and Development Co. Ltd. (IL) 2014-09-10 EP disclosed
WO-2013065048-A1 TRANSGENIC PLANTS RESISTANT TO NON-PROTEIN AMINO ACIDS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2013-05-10 WO disclosed