SCHEMBL458080

SCHEMBL458080

NC(Cc1cccc(O)c1)C(=O)O

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 1/20 0.82
SLC7A5 Q01650 7/20 0.67
PTGS1 P23219 2/20 0.67
ALPI P09923 1/20 0.67
PKM P14618 1/20 0.67
XIAP P98170 1/20 0.67
KDM4E B2RXH2 1/20 0.62
USP2 O75604 1/20 0.62
EGFR P00533 1/20 0.62
LCK P06239 1/20 0.62
FYN P06241 1/20 0.62
ADORA3 P0DMS8 1/20 0.62
ALOX15 P16050 1/20 0.62
HTR2A P28223 1/20 0.62
PTGS2 P35354 1/20 0.62
RECQL P46063 1/20 0.62
HIF1A Q16665 1/20 0.62
HSD17B10 Q99714 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
NOS3 P29474 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4356402 1.00 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL22721343 1.00 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL31453795 1.00 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL29430938 1.00 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL147042 1.00 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL13537526 1.00 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
Ammonia Solution, Strong SCHEMBL14919922 0.98 GRIA2 (0.79) GRIA2SLC7A5PTGS1ALPIPKM
Hydrochloric Acid SCHEMBL6491326 0.98 GRIA2 (0.79) GRIA2SLC7A5PTGS1ALPIPKM
Hydrochloric Acid SCHEMBL6491324 0.98 GRIA2 (0.79) GRIA2SLC7A5PTGS1ALPIPKM
Hydrochloric Acid SCHEMBL6491317 0.98 GRIA2 (0.79) GRIA2SLC7A5PTGS1ALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 801 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070294-A Stable vitreous material based on histidine, arginine and glutamic acid amino acids 阵序补丁有限公司 2026-05-19 CN claimed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US claimed
CN-119424050-A Degradable valve frame and heart valve 元心科技(深圳)有限公司 2025-02-14 CN claimed
WO-2025026273-A1 DEGRADABLE VALVE STENT, VALVE STENT FOR PULMONARY ARTERIAL VALVE, PULMONARY ARTERIAL VALVE, AND HEART VALVE 元心科技(深圳)有限公司 2025-02-06 WO claimed
EP-3655036-B1 COMPOSITIONS FOR TREATING STRESS-RELATED DISORDERS HOFFMAN TECH LLC (US) 2024-09-04 EP claimed
CN-118225136-B Multifunctional flexible sensor and preparation method thereof 齐鲁工业大学(山东省科学院) 2024-08-16 CN claimed
CN-118225136-A Multifunctional flexible sensor and preparation method thereof 齐鲁工业大学(山东省科学院) 2024-06-21 CN claimed
US-11931329-B2 Compositions and methods for treating anxiety-related disorders YAMO PHARMACEUTICALS LLC (US) 2024-03-19 US claimed
US-20240024268-A1 Methods for Dopamine Modulation in Human Neurologic Diseases SACKNER BERNSTEIN JONATHAN (US) 2024-01-25 US claimed
US-7265146-B2 Integrin receptor inhibitors GENENTECH, INC. (US) 2007-09-04 US claimed
US-20070178554-A1 Orthogonal Aminoacyl Synthetase-tRNA Pairs for Incorporating Unnatural Amino Acids Into Proteins NEURION PHARMACEUTICALS, INC. 2007-08-02 US claimed
WO-2006039717-A2 METHODS OF DETERMINING PRECISE HERG INTERACTIONS AND ALTERING COMPOUNDS BASED ON SAID INTERACTIONS NEURION PHARMACEUTICALS, INC. (US) 2006-04-13 WO claimed
US-20050187284-A1 Integrin receptor inhibitors GENENTECH, INC. (US) 2005-08-25 US claimed
EP-1330430-A2 INTEGRIN RECEPTOR INHIBITORS GENENTECH, INC. (US) 2003-07-30 EP claimed
US-20020035104-A1 Integrin receptor inhibitors GENENTECH, INC. 2002-03-21 US claimed
WO-2002016313-A2 INTEGRIN RECEPTOR INHIBITORS GENENTECH, INC. (US) 2002-02-28 WO claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed
EP-0672148-A1 METHOD FOR MAKING STABLE, EXTRACELLULAR TYROSINASE AND SYNTHESIS OF POLYPHENOLIC POLYMERS THEREFROM Biosource Technologies, Inc. (US) 1995-09-20 EP claimed
WO-1994012644-A2 METHOD FOR MAKING STABLE, EXTRACELLULAR TYROSINASE AND SYNTHESIS OF POLYPHENOLIC POLYMERS THEREFROM BIOSOURCE GENETICS CORPORATION (US) 1994-06-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM GRIA2 2633/4885SLC7A5 1166/4885PTGS1 2925/4885
US-20020035104-A1 Integrin receptor inhibitors ITGB1, ITGA1, ITGA4 GRIA2 1429/4885SLC7A5 4309/4885PTGS1 2112/4885
US-20070178554-A1 Orthogonal Aminoacyl Synthetase-tRNA Pairs for Incorporating Unnatural Amino Acids Into Proteins AARS1, GARS1, TRMT1 GRIA2 2576/4885SLC7A5 171/4885PTGS1 4347/4885
US-20050187284-A1 Integrin receptor inhibitors ITGA4, ITGB4, ITGB1 GRIA2 1788/4885SLC7A5 3877/4885PTGS1 3677/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT GRIA2 1018/4885SLC7A5 64/4885PTGS1 3489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.