SCHEMBL4356402

SCHEMBL4356402

N[C@H](Cc1cccc(O)c1)C(=O)O

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 1/20 0.82
SLC7A5 Q01650 7/20 0.67
PTGS1 P23219 2/20 0.67
ALPI P09923 1/20 0.67
PKM P14618 1/20 0.67
XIAP P98170 1/20 0.67
KDM4E B2RXH2 1/20 0.62
USP2 O75604 1/20 0.62
EGFR P00533 1/20 0.62
LCK P06239 1/20 0.62
FYN P06241 1/20 0.62
ADORA3 P0DMS8 1/20 0.62
ALOX15 P16050 1/20 0.62
HTR2A P28223 1/20 0.62
PTGS2 P35354 1/20 0.62
RECQL P46063 1/20 0.62
HIF1A Q16665 1/20 0.62
HSD17B10 Q99714 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
NOS3 P29474 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22721343 1.00 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL31453795 1.00 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL29430938 1.00 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL147042 1.00 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL458080 1.00 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
SCHEMBL13537526 1.00 GRIA2 (0.82) GRIA2SLC7A5PTGS1ALPIPKM
Ammonia Solution, Strong SCHEMBL14919922 0.98 GRIA2 (0.79) GRIA2SLC7A5PTGS1ALPIPKM
Hydrochloric Acid SCHEMBL6491326 0.98 GRIA2 (0.79) GRIA2SLC7A5PTGS1ALPIPKM
Hydrochloric Acid SCHEMBL6491324 0.98 GRIA2 (0.79) GRIA2SLC7A5PTGS1ALPIPKM
Hydrochloric Acid SCHEMBL6491317 0.98 GRIA2 (0.79) GRIA2SLC7A5PTGS1ALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070294-A Stable vitreous material based on histidine, arginine and glutamic acid amino acids 阵序补丁有限公司 2026-05-19 CN claimed
CN-118225136-B Multifunctional flexible sensor and preparation method thereof 齐鲁工业大学(山东省科学院) 2024-08-16 CN claimed
CN-118225136-A Multifunctional flexible sensor and preparation method thereof 齐鲁工业大学(山东省科学院) 2024-06-21 CN claimed
CN-115851645-A Proteobacterium vulgaris meso-diaminopimelate dehydrogenase mutant and application thereof 江南大学 2023-03-28 CN claimed
US-20200146989-A1 A CO-AMORPHOUS FORM OF A SUBSTANCE AND A DIPEPTIDE UNIVERSITY OF COPENHAGEN (DK) 2020-05-14 US claimed
EP-3559016-A1 A CO-AMORPHOUS FORM OF A SUBSTANCE AND A DIPEPTIDE University of Copenhagen (DK) 2019-10-30 EP claimed
WO-2018113891-A1 A CO-AMORPHOUS FORM OF A SUBSTANCE AND A DIPEPTIDE UNIVERSITY OF COPENHAGEN (DK) 2018-06-28 WO claimed
CN-122070294-A Stable vitreous material based on histidine, arginine and glutamic acid amino acids 阵序补丁有限公司 2026-05-19 CN disclosed
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS SERVIER LAB (FR) 2026-01-01 US disclosed
CN-119816491-A New spirocyclohexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors 法国施维雅药厂 2025-04-11 CN disclosed
CN-118225136-B Multifunctional flexible sensor and preparation method thereof 齐鲁工业大学(山东省科学院) 2024-08-16 CN disclosed
CN-118225136-B Multifunctional flexible sensor and preparation method thereof 齐鲁工业大学(山东省科学院) 2024-08-16 CN disclosed
CN-118225136-A Multifunctional flexible sensor and preparation method thereof 齐鲁工业大学(山东省科学院) 2024-06-21 CN disclosed
US-7649015-B2 Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds GILEAD SCIENCES, INC. (US) 2010-01-19 US disclosed
US-7618978-B2 Amides as BACE inhibitors ELI LILLY AND COMPANY (US) 2009-11-17 US disclosed
US-20070225372-A1 Amides as Bace Inhibitors ELI LILLY AND COMPANY 2007-09-27 US disclosed
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds GILEAD SCIENCES, INC. 2007-01-11 US disclosed
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds GILEAD SCIENCES, INC. 2007-01-11 US disclosed
EP-1740573-A1 AMIDES AS BACE INHIBITORS ELI LILLY AND COMPANY (US) 2007-01-10 EP disclosed
WO-2005108391-A1 AMIDES AS BACE INHIBITORS ELI LILLY AND COMPANY (US) 2005-11-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070225372-A1 Amides as Bace Inhibitors BACE2, BACE1, APP GRIA2 1832/4885SLC7A5 3429/4885PTGS1 2327/4885
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS BCL2, BCL2A1, BAX GRIA2 3324/4885SLC7A5 3306/4885PTGS1 143/4885
US-20200146989-A1 A CO-AMORPHOUS FORM OF A SUBSTANCE AND A DIPEPTIDE DNPEP, PEPD, IDUA GRIA2 3000/4885SLC7A5 436/4885PTGS1 4309/4885
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds PPA1, PNP, PPME1 GRIA2 4538/4885SLC7A5 1918/4885PTGS1 3372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.