Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL8432661 | 0.94 | ALDH1A1 (0.42) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL28393262 | 0.94 | ALDH1A1 (0.50) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL7115101 | 0.94 | ALDH1A1 (0.50) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL20338904 | 0.94 | ALDH1A1 (0.50) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL115545 | 0.94 | — | — | |
| Ether SCHEMBL28328411 | 0.94 | ALDH1A1 (0.50) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL271068 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL151167 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL11311472 | 0.90 | ALDH1A1 (0.48) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL17766472 | 0.90 | ALDH1A1 (0.48) | ALDH1A1TSHRFFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240034828-A1 | Aqueous Polyurethane Urea Dispersion | COVESTRO DEUTSCHLAND AG (DE) | 2024-02-01 | — | — | US | disclosed |
| EP-4259683-A1 | AQUEOUS POLYURETHANE UREA DISPERSION | Covestro Deutschland AG (DE) | 2023-10-18 | — | — | EP | disclosed |
| CN-116601201-A | Aqueous polyurethane urea dispersions | 科思创德国股份有限公司 | 2023-08-15 | — | — | CN | disclosed |
| EP-4029894-A1 | AQUEOUS POLYURETHANE UREA DISPERSION | Covestro Deutschland AG (DE) | 2022-07-20 | — | — | EP | disclosed |
| WO-2022122567-A1 | AQUEOUS POLYURETHANE UREA DISPERSION | COVESTRO DEUTSCHLAND AG (DE) | 2022-06-16 | — | — | WO | disclosed |
| CN-114605611-A | Aqueous polyurethane urea dispersions | 科思创德国股份有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-104357951-A | Cotton fiber for heat-insulating and sound-absorbing materials for buildings and producing method of cotton fiber | ANHUI YINGYUAN AGRICULTURAL TECHNOLOGY CO LTD | 2015-02-18 | — | — | CN | disclosed |
| CN-102964967-A | Anticorrosive coating | Qingdao xuanwei coating material co ltd | 2013-03-13 | — | — | CN | disclosed |
| US-8034122-B2 | Bleaching agent comprising 2-acylpyridinium derivatives | HENKEL AG & CO. KGAA (DE) | 2011-10-11 | — | — | US | disclosed |
| US-7981166-B2 | Bleaching agent having cationic acyl pyridinium derivatives, co-bleaching activators and hydrogen peroxide | HENKEL AG & CO. KGAA (DE) | 2011-07-19 | — | — | US | disclosed |
| US-20110162671-A1 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2011-07-07 | — | — | US | disclosed |
| US-20110047712-A1 | BLEACHING AGENT HAVING CATIONIC ACYL PYRIDINIUM DERATIVES, CO-BLEACHING ACTIVATORS AND HYDROGEN PEROXIDE | HENKEL AG & CO. KGAA (DE) | 2011-03-03 | — | — | US | disclosed |
| CN-1079283-C | Load type laminated zirconium sulfate catalyst and its application in preparation of aliphatic alcohol ether acetate | BEIJING UNIV OF CHEMICAL ENGIN (CN) | 2002-02-20 | — | — | CN | disclosed |
| EP-1015033-A2 | SUBSTITUTED PERYLENEQUINONES FOR USE IN PHOTODYNAMIC THERAPY | AltaRex, Corp. (CA) | 2000-07-05 | — | — | EP | disclosed |
| EP-1015033-A4 | SUBSTITUTED PERYLENEQUINONES FOR USE IN PHOTODYNAMIC THERAPY | ALTAREX INC (CA) | 2000-07-05 | — | — | EP | disclosed |
| CN-1253856-A | Load type laminated zirconium sulfate catalyst and its application in preparation of aliphatic alcohol ether acetate | BEIJING UNIV OF CHEMICAL ENGIN (CN) | 2000-05-24 | — | — | CN | disclosed |
| WO-1998033470-A2 | SUBSTITUTED PERYLENEQUINONES FOR USE IN PHOTODYNAMIC THERAPY | ALTAREX CORP. (CA) | 1998-08-06 | — | — | WO | disclosed |
| CN-1043177-A | Carry out the method for dyeing keratinous fibres and new 1,4-benzoquinones with oxyindole and quinone derivative | OREAL (FR) | 1990-06-20 | — | — | CN | disclosed |
| US-4556744-A | Process for the production of ethanol and/or acetaldehyde by the metal catalysed liquid phase reaction of methanol, carbon monoxide and hydrogen in the presence of a solvent | THE BRITISH PETROLEUM COMPANY P.L.C. (GB) | 1985-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110047712-A1 | BLEACHING AGENT HAVING CATIONIC ACYL PYRIDINIUM DERATIVES, CO-BLEACHING ACTIVATORS AND HYDROGEN PEROXIDE | F12, KRT18, H1-3 | ALDH1A1 980/4885TSHR 2090/4885FFAR3 648/4885 |
| US-20110162671-A1 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | KRT18, CBR3, ACOX3 | ALDH1A1 401/4885TSHR 2327/4885FFAR3 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.